Polyisoprene Rubber Gaskets
Polyisoprene is the synthetic equivalent of natural rubber, offering similar mechanical properties without the variability and latex protein content of plant-derived natural rubber. Cannon Gasket die-cuts custom polyisoprene gaskets for medical, food, and industrial applications where consistent chemistry and FDA compliance matter.
- Durometer
- 30A to 80A
- Highlight
- Latex-free alternative

Request a quote for Polyisoprene gaskets.
Properties of Polyisoprene gaskets
Cannon Gasket cuts Polyisoprene gaskets to your specifications in durometers ranging from 20A to 80A Shore hardness. Polyisoprene exhibits resistance to water, dilute acids, and alcohols.
Polyisoprene tolerances and customization
Standard dimensional tolerances on Polyisoprene gaskets land around ±0.010" to ±0.015" on OD and ID, depending on material durometer and thickness. Tighter tolerances are available on selected grades. Cannon Gasket cuts Polyisoprene to custom profiles in-house and matches lead times to your production volume. PSA backing, pad printing, custom packaging, and kitting are all on the menu when you need them.
How Polyisoprene Performs
- Mechanical properties similar to natural rubber — high resilience, good tear strength, low compression set. - Latex-protein-free formulations available for medical use. - FDA and medical-grade compounds available.
Where Polyisoprene Gaskets Are Specified
Medical device gaskets, pharmaceutical equipment, food and beverage seals, latex-sensitive applications, and assemblies where natural rubber's chemistry is desired without the inconsistency of plant-derived stock.
When to Choose Another Material
For oil contact specify Buna-N. For outdoor / ozone exposure specify EPDM. For high temperature specify silicone.
Manufacturing Methods
Die-cut. Clean room production available for medical-grade applications.
Standard sizes, tolerances & manufacturing
Precision & tooling: Capable of holding tolerances as tight as ±.001" on critical dimensions when required, beyond the ±0.010" to ±0.015" standard. Short- and long-run capabilities. All parts available with pressure-sensitive adhesive (PSA) on one or two sides.
Clean room: Cannon Gasket offers clean-environment stamping for medical, FDA, electronic, and scientific applications where a controlled level of particulate is required, with capabilities to meet ISO Class 10,000.
Stocking agreements: Blanket orders, VMI (vendor-managed inventory), JIT (just-in-time), and Kanban replenishment programs.
Pad printing: Pad print your part number, identification marking, or company name in a range of ink colors. Marking per customer specifications or MIL-STD-130.
Packaging: Parts are bagged and tagged in specified quantities and labeled with P/N or any required information. Capability to meet specific packaging and labeling requirements.
Standard RMA Thicknesses and Tolerances for Elastomers
| Nominal Thickness | Tolerance |
|---|---|
| 0.015" | ±0.010" |
| 0.031" | ±0.012" |
| 0.062" | ±0.016" |
| 0.093" | ±0.016" |
| 0.125" | ±0.020" |
| 0.187" | ±0.031" |
| 0.250" | ±0.031" |
| 0.375" | ±0.047" |
| 0.500" | ±0.047" |
Standard references shown. Cannon Gasket also cuts custom outside diameters, inside diameters, and thicknesses to your drawing. Send your specifications for a quote.